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OCR: e due to Patients with the ectopic ACTH syndrom Tary low-grade malignancies, such as a medu pancreatic thyroid carcinoma, carcinoid tumours o ires of endocrine tumours, develop typical feat its survive Cushing's syndrome, because such patie blown for a sufficient period to develop the ful syndrome. nancies, However, in the case of high-grade mal and such as small-cell carcinomas of the lun apidly uterus, the patient's condition becomes e to worse, which in turn makes it impossib tients develop typical physical changes; such p balance, frequently present only an electrolyte in ntation. metabolic derangement and hyperpigme See also: . Thyroid Malignancy mdrome . Aetiology of Spontaneous Cushing's